南非卫生部表示，正准备在10月之前为550万名60岁以上的人群接种疫苗。
南非官方COVID-19疫苗接种计划注册门户网站于4月16日星期五启动。
卫生部长兹维利·姆赫兹（Zweli Mkhize）正在进行全国巡视，以评估各省准备进行大规模疫苗接种计划的进行。
以下是豪登省的疫苗接种中心：
Chris Hani Baragwanath Hospital
26 Chris Hani Rd, Diepkloof 319-Iq, Johannesburg, 1864
Steve Biko Academic Hospital
Steve Biko and, Malan St, Capital Park, Pretoria
Ahmed Kathrada Private Hospital
K43 Klipspruit West Lenasia, Soweto, 1821
Charlotte Maxeke Hospital
5 Jubilee Rd, Parktown, Johannesburg, 2196
Dr George Mukhari Hospital
3111 Setlogelo Drive, Ga-Rankuwa Unit 2, Ga-Rankuwa, 0208
Netcare Milpark Hospital
9 Guild Road, Parktown West, Johannesburg, 2193
以下是西开普省的疫苗接种中心：
Groote Schuur Hospital
Groote Schuur Hospital, Main Road, Observatory, 7935
Tygerberg Hospital
Francie Van Zijl Dr, Avenue, Cape Town, 7505
Khayelitsha District Hospital
Cnr Walter Sisulu & Steve Biko Road, Khayelitsha, Cape Town, 7784
Mitchells Plain hospital
8 A Z Berman Dr, Lentegeur, Cape Town, 7785
Gatesville Melomed
Clinic St, Gatesville, Cape Town, 7764
George Hospital
King George Park Corner of Davidson andLangenhoven Road, Heatherlands, George, 6530
Karl Bremmer Hospital
Frans Conradie Dr, Bellville West, Cape Town
Paarl Hospital
Corner of Hospital and Bergriver Boulevard, Paarl, 7646
Worcester Hospital
Murray Street, Worcester, 6849
以下是夸祖鲁纳塔尔省的疫苗接种中心：
Inkosi Albert Luthuli Central Hospital
800 Vusi Mzimela Rd, Umkumbaan, Durban, 4091
Prince Mshiyeni Memorial Hospital
Griffiths Mxenge Hwy, Umlazi V, Umlazi, 4060
General Justice Gizenga Mpanza
Cnr King Shaka & Paterson Street, Kwadukuza, 4449
Edendale Hospital
89 Selby Msimang Rd, Plessislaer, Pietermaritzburg, 3201
Madadeni Hospital
Madadeni Road, Madadeni, Newcastle, 2951
Netcare St. Augustine's Hospital
107 J.B. Marks Rd, Bulwer, Berea, 4001